Alteration of the Neuromuscular Junction and Modifications of Muscle Metabolism in Response to Neuron-Restricted Expression of the CHMP2B(intron5) Mutant in a Mouse Model of ALS-FTD Syndrome

CHMP2B is a protein that coordinates membrane scission events as a core component of the ESCRT machinery. Mutations in CHMP2B are an uncommon cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two neurodegenerative diseases with clinical, genetic, and pathological overla...

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Autores principales: Waegaert, Robin, Dirrig-Grosch, Sylvie, Liu, Haoyi, Boutry, Marion, Luan, Ping, Loeffler, Jean-Philippe, René, Frédérique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025139/
https://www.ncbi.nlm.nih.gov/pubmed/35454086
http://dx.doi.org/10.3390/biom12040497

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