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SRSF6 Regulates the Alternative Splicing of the Apoptotic Fas Gene by Targeting a Novel RNA Sequence

SIMPLE SUMMARY: Alternative splicing (AS) produces multiple mRNA isoforms from a gene to make a large number of proteins. Fas (Apo-1/CD95) pre-mRNA, a member of TNF receptor family that mediates apoptosis, can generate pro-apoptotic and anti-apoptotic proteins through AS. Here, we identified SRSF6 a...

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Detalles Bibliográficos
Autores principales: Choi, Namjeong, Jang, Ha Na, Oh, Jagyeong, Ha, Jiyeon, Park, Hyungbin, Zheng, Xuexiu, Lee, Sunjae, Shen, Haihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025165/
https://www.ncbi.nlm.nih.gov/pubmed/35454897
http://dx.doi.org/10.3390/cancers14081990

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