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Is Increased Resting Heart Rate after Radiofrequency Pulmonary Vein Isolation a Predictor of Favorable Long-Term Outcome of the Procedure?

Background: Increased resting heart rate (RHR) after pulmonary vein isolation (PVI) for treatment of atrial fibrillation (AF) is a common observation, possibly resulting from ganglionated plexus modification during ablation. Previous trials have suggested that an increase in RHR after ablation might...

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Autores principales: Maciejewski, Cezary, Peller, Michał, Lodziński, Piotr, Koźluk, Edward, Piątkowska, Agnieszka, Rodkiewicz, Dariusz, Sierakowska, Izabela, Roman, Natalia, Wiśniewska, Diana, Żółcińska, Dominika, Rymaszewska, Dominika, Opolski, Grzegorz, Grabowski, Marcin, Balsam, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025177/
https://www.ncbi.nlm.nih.gov/pubmed/35456252
http://dx.doi.org/10.3390/jcm11082159
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author Maciejewski, Cezary
Peller, Michał
Lodziński, Piotr
Koźluk, Edward
Piątkowska, Agnieszka
Rodkiewicz, Dariusz
Sierakowska, Izabela
Roman, Natalia
Wiśniewska, Diana
Żółcińska, Dominika
Rymaszewska, Dominika
Opolski, Grzegorz
Grabowski, Marcin
Balsam, Paweł
author_facet Maciejewski, Cezary
Peller, Michał
Lodziński, Piotr
Koźluk, Edward
Piątkowska, Agnieszka
Rodkiewicz, Dariusz
Sierakowska, Izabela
Roman, Natalia
Wiśniewska, Diana
Żółcińska, Dominika
Rymaszewska, Dominika
Opolski, Grzegorz
Grabowski, Marcin
Balsam, Paweł
author_sort Maciejewski, Cezary
collection PubMed
description Background: Increased resting heart rate (RHR) after pulmonary vein isolation (PVI) for treatment of atrial fibrillation (AF) is a common observation, possibly resulting from ganglionated plexus modification during ablation. Previous trials have suggested that an increase in RHR after ablation might be related to higher efficacy of the procedure. The aim of this study was to determine whether or not higher increase in RHR after radiofrequency (RF) PVI might predict better long-term outcome of the procedure in a real-life cohort of patients in whom index ablation for paroxysmal AF was performed. Material and methods: The health records of patients who underwent index point-by-point or drag lesion RF PVI for paroxysmal AF in our department between January 2014 and November 2018 were analyzed. Resting heart rate (RHR) was determined from 12-lead ECG recorded prior to the ablation and before discharge to evaluate changes in RHR after PVI. Only patients in sinus rhythm before the procedure and at discharge were included in the analysis. Telephone follow-up was collected for evaluation of arrhythmia recurrence status. Results: A total of 146 patients who underwent PVI for paroxysmal AF were included. Mean follow-up time was 3.5 years. RHR increased from 64 [58.5–70], prior to procedure, to 72 [64.25–80] bpm at discharge (p < 0.001). Higher increase in RHR was not protective from arrhythmia recurrence in long-term observation in both univariable HR = 1.001 (CI 0.99–1.017, p = 0.857) and multivariable analyses HR = 1.001 (CI 0.99–1.02, p = 0.84). Conclusions: RHR after PVI increased in comparison to baseline in our cohort. However, we did not observe higher increase in RHR to be associated with more favorable long-term effectiveness of the procedure.
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spelling pubmed-90251772022-04-23 Is Increased Resting Heart Rate after Radiofrequency Pulmonary Vein Isolation a Predictor of Favorable Long-Term Outcome of the Procedure? Maciejewski, Cezary Peller, Michał Lodziński, Piotr Koźluk, Edward Piątkowska, Agnieszka Rodkiewicz, Dariusz Sierakowska, Izabela Roman, Natalia Wiśniewska, Diana Żółcińska, Dominika Rymaszewska, Dominika Opolski, Grzegorz Grabowski, Marcin Balsam, Paweł J Clin Med Article Background: Increased resting heart rate (RHR) after pulmonary vein isolation (PVI) for treatment of atrial fibrillation (AF) is a common observation, possibly resulting from ganglionated plexus modification during ablation. Previous trials have suggested that an increase in RHR after ablation might be related to higher efficacy of the procedure. The aim of this study was to determine whether or not higher increase in RHR after radiofrequency (RF) PVI might predict better long-term outcome of the procedure in a real-life cohort of patients in whom index ablation for paroxysmal AF was performed. Material and methods: The health records of patients who underwent index point-by-point or drag lesion RF PVI for paroxysmal AF in our department between January 2014 and November 2018 were analyzed. Resting heart rate (RHR) was determined from 12-lead ECG recorded prior to the ablation and before discharge to evaluate changes in RHR after PVI. Only patients in sinus rhythm before the procedure and at discharge were included in the analysis. Telephone follow-up was collected for evaluation of arrhythmia recurrence status. Results: A total of 146 patients who underwent PVI for paroxysmal AF were included. Mean follow-up time was 3.5 years. RHR increased from 64 [58.5–70], prior to procedure, to 72 [64.25–80] bpm at discharge (p < 0.001). Higher increase in RHR was not protective from arrhythmia recurrence in long-term observation in both univariable HR = 1.001 (CI 0.99–1.017, p = 0.857) and multivariable analyses HR = 1.001 (CI 0.99–1.02, p = 0.84). Conclusions: RHR after PVI increased in comparison to baseline in our cohort. However, we did not observe higher increase in RHR to be associated with more favorable long-term effectiveness of the procedure. MDPI 2022-04-12 /pmc/articles/PMC9025177/ /pubmed/35456252 http://dx.doi.org/10.3390/jcm11082159 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Maciejewski, Cezary
Peller, Michał
Lodziński, Piotr
Koźluk, Edward
Piątkowska, Agnieszka
Rodkiewicz, Dariusz
Sierakowska, Izabela
Roman, Natalia
Wiśniewska, Diana
Żółcińska, Dominika
Rymaszewska, Dominika
Opolski, Grzegorz
Grabowski, Marcin
Balsam, Paweł
Is Increased Resting Heart Rate after Radiofrequency Pulmonary Vein Isolation a Predictor of Favorable Long-Term Outcome of the Procedure?
title Is Increased Resting Heart Rate after Radiofrequency Pulmonary Vein Isolation a Predictor of Favorable Long-Term Outcome of the Procedure?
title_full Is Increased Resting Heart Rate after Radiofrequency Pulmonary Vein Isolation a Predictor of Favorable Long-Term Outcome of the Procedure?
title_fullStr Is Increased Resting Heart Rate after Radiofrequency Pulmonary Vein Isolation a Predictor of Favorable Long-Term Outcome of the Procedure?
title_full_unstemmed Is Increased Resting Heart Rate after Radiofrequency Pulmonary Vein Isolation a Predictor of Favorable Long-Term Outcome of the Procedure?
title_short Is Increased Resting Heart Rate after Radiofrequency Pulmonary Vein Isolation a Predictor of Favorable Long-Term Outcome of the Procedure?
title_sort is increased resting heart rate after radiofrequency pulmonary vein isolation a predictor of favorable long-term outcome of the procedure?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025177/
https://www.ncbi.nlm.nih.gov/pubmed/35456252
http://dx.doi.org/10.3390/jcm11082159
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