Chronic Myelogenous Leukemia with Double Philadelphia Chromosome and Coexpression of p210 and p190 Fusion Transcripts

The Philadelphia (Ph+) chromosome, t(9;22)(q34;q11.2), originates from a chimeric gene called BCR-ABL and is present in more than 90% of CML patients. Most patients with CML express the protein p210 BCR-ABL and, with a frequency lower than 5%, express rare isoforms, the main one being p190. In the t...

Descripción completa

Detalles Bibliográficos
Autores principales: da Cruz, Samara Silveira, Seabra, Aline Damasceno, Macambira, Lais Helena Rescinho, Carneiro, Débora Monteiro, Nunes, Patrícia Ferreira, Pontes, Thais Brilhante, Mello-Junior, Fernando Augusto Rodrigues, Leão, Lucyana Barbosa Cardoso, Cordeiro, Fernanda de Nazaré Cardoso dos Santos, Carneiro, Thiago Xavier, Moreira-Nunes, Caroline Aquino, Burbano, Rommel Mario Rodríguez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025354/
https://www.ncbi.nlm.nih.gov/pubmed/35456386
http://dx.doi.org/10.3390/genes13040580

Ejemplares similares

Ejemplares similares