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An Olive-Derived Extract 20% Rich in Hydroxytyrosol Prevents β-Amyloid Aggregation and Oxidative Stress, Two Features of Alzheimer Disease, via SKN-1/NRF2 and HSP-16.2 in Caenorhabditis elegans

Olive milling produces olive oil and different by-products, all of them very rich in different bioactive compounds like the phenolic alcohol hydroxytyrosol. The aim of the present study was to investigate the effects of an olive fruit extract 20% rich in hydroxytyrosol on the molecular mechanisms as...

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Detalles Bibliográficos
Autores principales: Romero-Márquez, Jose M., Navarro-Hortal, María D., Jiménez-Trigo, Victoria, Muñoz-Ollero, Pedro, Forbes-Hernández, Tamara Y., Esteban-Muñoz, Adelaida, Giampieri, Francesca, Delgado Noya, Irene, Bullón, Pedro, Vera-Ramírez, Laura, Battino, Maurizio, Sánchez-González, Cristina, Quiles, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025619/
https://www.ncbi.nlm.nih.gov/pubmed/35453314
http://dx.doi.org/10.3390/antiox11040629