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An Olive-Derived Extract 20% Rich in Hydroxytyrosol Prevents β-Amyloid Aggregation and Oxidative Stress, Two Features of Alzheimer Disease, via SKN-1/NRF2 and HSP-16.2 in Caenorhabditis elegans
Olive milling produces olive oil and different by-products, all of them very rich in different bioactive compounds like the phenolic alcohol hydroxytyrosol. The aim of the present study was to investigate the effects of an olive fruit extract 20% rich in hydroxytyrosol on the molecular mechanisms as...
Autores principales: | Romero-Márquez, Jose M., Navarro-Hortal, María D., Jiménez-Trigo, Victoria, Muñoz-Ollero, Pedro, Forbes-Hernández, Tamara Y., Esteban-Muñoz, Adelaida, Giampieri, Francesca, Delgado Noya, Irene, Bullón, Pedro, Vera-Ramírez, Laura, Battino, Maurizio, Sánchez-González, Cristina, Quiles, José L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025619/ https://www.ncbi.nlm.nih.gov/pubmed/35453314 http://dx.doi.org/10.3390/antiox11040629 |
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