Evidence for a Strong Relationship between the Cytotoxicity and Intracellular Location of β-Amyloid

β-Amyloid (Aβ) is a hallmark peptide of Alzheimer’s disease (AD). Herein, we explored the mechanism underlying the cytotoxicity of this peptide. Double treatment with oligomeric 42-amino-acid Aβ (Aβ42) species, which are more cytotoxic than other conformers such as monomers and fibrils, resulted in...

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Detalles Bibliográficos
Autores principales: Haque, Md. Aminul, Hossain, Md. Selim, Bilkis, Tahmina, Islam, Md. Imamul, Park, Il-Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025630/
https://www.ncbi.nlm.nih.gov/pubmed/35455068
http://dx.doi.org/10.3390/life12040577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025630/
https://www.ncbi.nlm.nih.gov/pubmed/35455068
http://dx.doi.org/10.3390/life12040577

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