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Diabetes Does Not Increase the Risk of Hospitalization Due to COVID-19 in Patients Aged 50 Years or Older in Primary Care—APHOSDIAB—COVID-19 Multicenter Study

The purpose of this study was to identify clinical, analytical, and sociodemographic variables associated with the need for hospital admission in people over 50 years infected with SARS-CoV-2 and to assess whether diabetes mellitus conditions the risk of hospitalization. A multicenter case-control s...

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Autores principales: Orozco-Beltrán, Domingo, Merino-Torres, Juan Francisco, Pérez, Antonio, Cebrián-Cuenca, Ana M., Párraga-Martínez, Ignacio, Ávila-Lachica, Luis, Rojo-Martínez, Gemma, Pomares-Gómez, Francisco J., Álvarez-Guisasola, Fernando, Sánchez-Molla, Manuel, Gutiérrez, Felix, Ortega, Francisco J., Mata-Cases, Manel, Carretero-Anibarro, Enrique, Vilaseca, Josep Maria, Quesada, Jose A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025638/
https://www.ncbi.nlm.nih.gov/pubmed/35456185
http://dx.doi.org/10.3390/jcm11082092
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author Orozco-Beltrán, Domingo
Merino-Torres, Juan Francisco
Pérez, Antonio
Cebrián-Cuenca, Ana M.
Párraga-Martínez, Ignacio
Ávila-Lachica, Luis
Rojo-Martínez, Gemma
Pomares-Gómez, Francisco J.
Álvarez-Guisasola, Fernando
Sánchez-Molla, Manuel
Gutiérrez, Felix
Ortega, Francisco J.
Mata-Cases, Manel
Carretero-Anibarro, Enrique
Vilaseca, Josep Maria
Quesada, Jose A.
author_facet Orozco-Beltrán, Domingo
Merino-Torres, Juan Francisco
Pérez, Antonio
Cebrián-Cuenca, Ana M.
Párraga-Martínez, Ignacio
Ávila-Lachica, Luis
Rojo-Martínez, Gemma
Pomares-Gómez, Francisco J.
Álvarez-Guisasola, Fernando
Sánchez-Molla, Manuel
Gutiérrez, Felix
Ortega, Francisco J.
Mata-Cases, Manel
Carretero-Anibarro, Enrique
Vilaseca, Josep Maria
Quesada, Jose A.
author_sort Orozco-Beltrán, Domingo
collection PubMed
description The purpose of this study was to identify clinical, analytical, and sociodemographic variables associated with the need for hospital admission in people over 50 years infected with SARS-CoV-2 and to assess whether diabetes mellitus conditions the risk of hospitalization. A multicenter case-control study analyzing electronic medical records in patients with COVID-19 from 1 March 2020 to 30 April 2021 was conducted. We included 790 patients: 295 cases admitted to the hospital and 495 controls. Under half (n = 386, 48.8%) were women, and 8.5% were active smokers. The main comorbidities were hypertension (50.5%), dyslipidemia, obesity, and diabetes (37.5%). Multivariable logistic regression showed that hospital admission was associated with age above 65 years (OR from 2.45 to 3.89, ascending with age group); male sex (OR 2.15, 95% CI 1.47–3.15), fever (OR 4.31, 95% CI 2.87–6.47), cough (OR 1.89, 95% CI 1.28–2.80), asthenia/malaise (OR 2.04, 95% CI 1.38–3.03), dyspnea (4.69, 95% CI 3.00–7.33), confusion (OR 8.87, 95% CI 1.68–46.78), and a history of hypertension (OR 1.61, 95% CI 1.08–2.41) or immunosuppression (OR 4.97, 95% CI 1.45–17.09). Diabetes was not associated with increased risk of hospital admission (OR 1.18, 95% CI 0.80–1.72; p = 0.38). Diabetes did not increase the risk of hospital admission in people over 50 years old, but advanced age, male sex, fever, cough, asthenia, dyspnea/confusion, and hypertension or immunosuppression did.
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spelling pubmed-90256382022-04-23 Diabetes Does Not Increase the Risk of Hospitalization Due to COVID-19 in Patients Aged 50 Years or Older in Primary Care—APHOSDIAB—COVID-19 Multicenter Study Orozco-Beltrán, Domingo Merino-Torres, Juan Francisco Pérez, Antonio Cebrián-Cuenca, Ana M. Párraga-Martínez, Ignacio Ávila-Lachica, Luis Rojo-Martínez, Gemma Pomares-Gómez, Francisco J. Álvarez-Guisasola, Fernando Sánchez-Molla, Manuel Gutiérrez, Felix Ortega, Francisco J. Mata-Cases, Manel Carretero-Anibarro, Enrique Vilaseca, Josep Maria Quesada, Jose A. J Clin Med Article The purpose of this study was to identify clinical, analytical, and sociodemographic variables associated with the need for hospital admission in people over 50 years infected with SARS-CoV-2 and to assess whether diabetes mellitus conditions the risk of hospitalization. A multicenter case-control study analyzing electronic medical records in patients with COVID-19 from 1 March 2020 to 30 April 2021 was conducted. We included 790 patients: 295 cases admitted to the hospital and 495 controls. Under half (n = 386, 48.8%) were women, and 8.5% were active smokers. The main comorbidities were hypertension (50.5%), dyslipidemia, obesity, and diabetes (37.5%). Multivariable logistic regression showed that hospital admission was associated with age above 65 years (OR from 2.45 to 3.89, ascending with age group); male sex (OR 2.15, 95% CI 1.47–3.15), fever (OR 4.31, 95% CI 2.87–6.47), cough (OR 1.89, 95% CI 1.28–2.80), asthenia/malaise (OR 2.04, 95% CI 1.38–3.03), dyspnea (4.69, 95% CI 3.00–7.33), confusion (OR 8.87, 95% CI 1.68–46.78), and a history of hypertension (OR 1.61, 95% CI 1.08–2.41) or immunosuppression (OR 4.97, 95% CI 1.45–17.09). Diabetes was not associated with increased risk of hospital admission (OR 1.18, 95% CI 0.80–1.72; p = 0.38). Diabetes did not increase the risk of hospital admission in people over 50 years old, but advanced age, male sex, fever, cough, asthenia, dyspnea/confusion, and hypertension or immunosuppression did. MDPI 2022-04-08 /pmc/articles/PMC9025638/ /pubmed/35456185 http://dx.doi.org/10.3390/jcm11082092 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Orozco-Beltrán, Domingo
Merino-Torres, Juan Francisco
Pérez, Antonio
Cebrián-Cuenca, Ana M.
Párraga-Martínez, Ignacio
Ávila-Lachica, Luis
Rojo-Martínez, Gemma
Pomares-Gómez, Francisco J.
Álvarez-Guisasola, Fernando
Sánchez-Molla, Manuel
Gutiérrez, Felix
Ortega, Francisco J.
Mata-Cases, Manel
Carretero-Anibarro, Enrique
Vilaseca, Josep Maria
Quesada, Jose A.
Diabetes Does Not Increase the Risk of Hospitalization Due to COVID-19 in Patients Aged 50 Years or Older in Primary Care—APHOSDIAB—COVID-19 Multicenter Study
title Diabetes Does Not Increase the Risk of Hospitalization Due to COVID-19 in Patients Aged 50 Years or Older in Primary Care—APHOSDIAB—COVID-19 Multicenter Study
title_full Diabetes Does Not Increase the Risk of Hospitalization Due to COVID-19 in Patients Aged 50 Years or Older in Primary Care—APHOSDIAB—COVID-19 Multicenter Study
title_fullStr Diabetes Does Not Increase the Risk of Hospitalization Due to COVID-19 in Patients Aged 50 Years or Older in Primary Care—APHOSDIAB—COVID-19 Multicenter Study
title_full_unstemmed Diabetes Does Not Increase the Risk of Hospitalization Due to COVID-19 in Patients Aged 50 Years or Older in Primary Care—APHOSDIAB—COVID-19 Multicenter Study
title_short Diabetes Does Not Increase the Risk of Hospitalization Due to COVID-19 in Patients Aged 50 Years or Older in Primary Care—APHOSDIAB—COVID-19 Multicenter Study
title_sort diabetes does not increase the risk of hospitalization due to covid-19 in patients aged 50 years or older in primary care—aphosdiab—covid-19 multicenter study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025638/
https://www.ncbi.nlm.nih.gov/pubmed/35456185
http://dx.doi.org/10.3390/jcm11082092
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