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Hydroxysafflor Yellow A Blocks HIF-1α Induction of NOX2 and Protects ZO-1 Protein in Cerebral Microvascular Endothelium

Zonula occludens-1 (ZO-1) is a tight junction protein in the cerebrovascular endothelium, responsible for blood–brain barrier function. Hydroxysafflor yellow A (HSYA) is a major ingredient of safflower (Carthamus tinctorius L.) with antioxidative activity. This study investigated whether HSYA protec...

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Detalles Bibliográficos
Autores principales: Li, Yi, Liu, Xiao-Tian, Zhang, Pei-Lin, Li, Yu-Chen, Sun, Meng-Ru, Wang, Yi-Tao, Wang, Sheng-Peng, Yang, Hua, Liu, Bao-Lin, Wang, Mei, Gao, Wen, Li, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025668/
https://www.ncbi.nlm.nih.gov/pubmed/35453413
http://dx.doi.org/10.3390/antiox11040728