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Brain Metabolite, Myo-inositol, Inhibits Catalase Activity: A Mechanism of the Distortion of the Antioxidant Defense System in Alzheimer’s disease

[Image: see text] A strong correlation between brain metabolite accumulation and oxidative stress has been observed in Alzheimer’s disease (AD) patients. There are two central hypotheses for this correlation: (i) coaccumulation of toxic amyloid-β and Myo-inositol (MI), a significant brain metabolite...

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Detalles Bibliográficos
Autores principales:	Ali, Fasil, Manzoor, Usma, Bhattacharya, Reshmee, Bansal, Aniket Kumar, Chandrashekharaiah, Kempohalli Sayanna, Singh, Laishram Rajendrakumar, Saraswati, Suma Mohan, Uversky, Vladimir, Dar, Tanveer Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025986/ https://www.ncbi.nlm.nih.gov/pubmed/35474814 http://dx.doi.org/10.1021/acsomega.1c06990

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