Selective Synthesis of Bis-Heterocycles via Mono- and Di-Selenylation of Pyrazoles and Other Heteroarenes

[Image: see text] The insertion of selenium was achieved in the form of mono-selenides and di-selenides for the preparation of novel bis-heterocyclic compounds. This method is more general and provides scaffold diversity with high yields of products. The concentration-dependent mono- and di-selenyla...

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Detalles Bibliográficos
Autores principales: Kour, Jaspreet, Khajuria, Pratiksha, Verma, Praveen Kumar, Kapoor, Neharika, Kumar, Amit, Sawant, Sanghapal D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026074/
https://www.ncbi.nlm.nih.gov/pubmed/35474812
http://dx.doi.org/10.1021/acsomega.2c00323
Descripción
Sumario:[Image: see text] The insertion of selenium was achieved in the form of mono-selenides and di-selenides for the preparation of novel bis-heterocyclic compounds. This method is more general and provides scaffold diversity with high yields of products. The concentration-dependent mono- and di-selenylation reaction selectivity was achieved using SeO(2) as an efficient selenylating reagent.

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