Selective Synthesis of Bis-Heterocycles via Mono- and Di-Selenylation of Pyrazoles and Other Heteroarenes

[Image: see text] The insertion of selenium was achieved in the form of mono-selenides and di-selenides for the preparation of novel bis-heterocyclic compounds. This method is more general and provides scaffold diversity with high yields of products. The concentration-dependent mono- and di-selenyla...

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Autores principales: Kour, Jaspreet, Khajuria, Pratiksha, Verma, Praveen Kumar, Kapoor, Neharika, Kumar, Amit, Sawant, Sanghapal D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026074/
https://www.ncbi.nlm.nih.gov/pubmed/35474812
http://dx.doi.org/10.1021/acsomega.2c00323
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author Kour, Jaspreet
Khajuria, Pratiksha
Verma, Praveen Kumar
Kapoor, Neharika
Kumar, Amit
Sawant, Sanghapal D.
author_facet Kour, Jaspreet
Khajuria, Pratiksha
Verma, Praveen Kumar
Kapoor, Neharika
Kumar, Amit
Sawant, Sanghapal D.
author_sort Kour, Jaspreet
collection PubMed
description [Image: see text] The insertion of selenium was achieved in the form of mono-selenides and di-selenides for the preparation of novel bis-heterocyclic compounds. This method is more general and provides scaffold diversity with high yields of products. The concentration-dependent mono- and di-selenylation reaction selectivity was achieved using SeO(2) as an efficient selenylating reagent.
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spelling pubmed-90260742022-04-25 Selective Synthesis of Bis-Heterocycles via Mono- and Di-Selenylation of Pyrazoles and Other Heteroarenes Kour, Jaspreet Khajuria, Pratiksha Verma, Praveen Kumar Kapoor, Neharika Kumar, Amit Sawant, Sanghapal D. ACS Omega [Image: see text] The insertion of selenium was achieved in the form of mono-selenides and di-selenides for the preparation of novel bis-heterocyclic compounds. This method is more general and provides scaffold diversity with high yields of products. The concentration-dependent mono- and di-selenylation reaction selectivity was achieved using SeO(2) as an efficient selenylating reagent. American Chemical Society 2022-04-08 /pmc/articles/PMC9026074/ /pubmed/35474812 http://dx.doi.org/10.1021/acsomega.2c00323 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Kour, Jaspreet
Khajuria, Pratiksha
Verma, Praveen Kumar
Kapoor, Neharika
Kumar, Amit
Sawant, Sanghapal D.
Selective Synthesis of Bis-Heterocycles via Mono- and Di-Selenylation of Pyrazoles and Other Heteroarenes
title Selective Synthesis of Bis-Heterocycles via Mono- and Di-Selenylation of Pyrazoles and Other Heteroarenes
title_full Selective Synthesis of Bis-Heterocycles via Mono- and Di-Selenylation of Pyrazoles and Other Heteroarenes
title_fullStr Selective Synthesis of Bis-Heterocycles via Mono- and Di-Selenylation of Pyrazoles and Other Heteroarenes
title_full_unstemmed Selective Synthesis of Bis-Heterocycles via Mono- and Di-Selenylation of Pyrazoles and Other Heteroarenes
title_short Selective Synthesis of Bis-Heterocycles via Mono- and Di-Selenylation of Pyrazoles and Other Heteroarenes
title_sort selective synthesis of bis-heterocycles via mono- and di-selenylation of pyrazoles and other heteroarenes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026074/
https://www.ncbi.nlm.nih.gov/pubmed/35474812
http://dx.doi.org/10.1021/acsomega.2c00323
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