In-Cell Quantification of Drugs by Magic-Angle Spinning Dynamic Nuclear Polarization NMR

[Image: see text] The determination of intracellular drug concentrations can provide a better understanding of the drug function and efficacy. Ideally, this should be performed nondestructively, with no modification of either the drug or the target, and with the capability to detect low amounts of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Bertarello, Andrea, Berruyer, Pierrick, Artelsmair, Markus, Elmore, Charles S., Heydarkhan-Hagvall, Sepideh, Schade, Markus, Chiarparin, Elisabetta, Schantz, Staffan, Emsley, Lyndon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026252/
https://www.ncbi.nlm.nih.gov/pubmed/35385274
http://dx.doi.org/10.1021/jacs.1c12442

Ejemplares similares

Ejemplares similares