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Peptide-Folding Triggered Phase Separation and Lipid Membrane Destabilization in Cholesterol-Rich Lipid Vesicles

[Image: see text] Liposome-based drug delivery systems are widely used to improve drug pharmacokinetics but can suffer from slow and unspecific release of encapsulated drugs. Membrane-active peptides, based on sequences derived or inspired from antimicrobial peptides (AMPs), could offer means to tri...

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Detalles Bibliográficos
Autores principales: Utterström, Johanna, Barriga, Hanna M. G., Holme, Margaret N., Selegård, Robert, Stevens, Molly M., Aili, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026255/
https://www.ncbi.nlm.nih.gov/pubmed/35362952
http://dx.doi.org/10.1021/acs.bioconjchem.2c00115

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