A Brain-Permeable Aminosterol Regulates Cell Membranes to Mitigate the Toxicity of Diverse Pore-Forming Agents

[Image: see text] The molecular composition of the plasma membrane plays a key role in mediating the susceptibility of cells to perturbations induced by toxic molecules. The pharmacological regulation of the properties of the cell membrane has therefore the potential to enhance cellular resilience t...

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Detalles Bibliográficos
Autores principales: Kreiser, Ryan P., Wright, Aidan K., Sasser, Liam R., Rinauro, Dillon J., Gabriel, Justus M., Hsu, Claire M., Hurtado, Jorge A., McKenzie, Tristan L., Errico, Silvia, Albright, J. Alex, Richardson, Lance, Jaffett, Victor A., Riegner, Dawn E., Nguyen, Lam T., LeForte, Kathleen, Zasloff, Michael, Hollows, Jared E., Chiti, Fabrizio, Vendruscolo, Michele, Limbocker, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026273/
https://www.ncbi.nlm.nih.gov/pubmed/35404569
http://dx.doi.org/10.1021/acschemneuro.1c00840

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