Pd-Catalyzed Heteroannulation Using N-Arylureas as a Sterically Undemanding Ligand Platform

[Image: see text] We report the development of ureas as sterically undemanding pro-ligands for Pd catalysis. N-Arylureas outperform phosphine ligands for the Pd-catalyzed heteroannulation of N-tosyl-o-bromoanilines and 1,3-dienes, engaging diverse coupling partners for the preparation of 2-subsitute...

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Detalles Bibliográficos
Autores principales: Vaith, Jakub, Rodina, Dasha, Spaulding, Gregory C., Paradine, Shauna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026275/
https://www.ncbi.nlm.nih.gov/pubmed/35380831
http://dx.doi.org/10.1021/jacs.2c01019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026275/
https://www.ncbi.nlm.nih.gov/pubmed/35380831
http://dx.doi.org/10.1021/jacs.2c01019

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