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Targeted Endoradiotherapy with Lu(2)O(3)-iPSMA/-iFAP Nanoparticles Activated by Neutron Irradiation: Preclinical Evaluation and First Patient Image

Prostate-specific membrane antigen (PSMA) is expressed in a variety of cancer cells, while the fibroblast activation protein (FAP) is expressed in the microenvironment of tumors. Previously, we reported the ability of iPSMA and iFAP ligands to specifically target PSMA and FAP proteins, as well as th...

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Detalles Bibliográficos
Autores principales: Luna-Gutiérrez, Myrna, Ocampo-García, Blanca, Jiménez-Mancilla, Nallely, Ancira-Cortez, Alejandra, Trujillo-Benítez, Diana, Hernández-Jiménez, Tania, Ramírez-Nava, Gerardo, Hernández-Ramírez, Rodrigo, Santos-Cuevas, Clara, Ferro-Flores, Guillermina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026501/
https://www.ncbi.nlm.nih.gov/pubmed/35456554
http://dx.doi.org/10.3390/pharmaceutics14040720