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Targeted Endoradiotherapy with Lu(2)O(3)-iPSMA/-iFAP Nanoparticles Activated by Neutron Irradiation: Preclinical Evaluation and First Patient Image
Prostate-specific membrane antigen (PSMA) is expressed in a variety of cancer cells, while the fibroblast activation protein (FAP) is expressed in the microenvironment of tumors. Previously, we reported the ability of iPSMA and iFAP ligands to specifically target PSMA and FAP proteins, as well as th...
Autores principales: | Luna-Gutiérrez, Myrna, Ocampo-García, Blanca, Jiménez-Mancilla, Nallely, Ancira-Cortez, Alejandra, Trujillo-Benítez, Diana, Hernández-Jiménez, Tania, Ramírez-Nava, Gerardo, Hernández-Ramírez, Rodrigo, Santos-Cuevas, Clara, Ferro-Flores, Guillermina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026501/ https://www.ncbi.nlm.nih.gov/pubmed/35456554 http://dx.doi.org/10.3390/pharmaceutics14040720 |
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