Dasiglucagon Effects on QTc in Healthy Volunteers: A Randomized, Placebo-Controlled, Dose-Escalation, Double-Blind Study

BACKGROUND: Dasiglucagon is a novel glucagon analog that is stable in aqueous formulation and approved for use in severe hypoglycemia. Concentration QTc analyses are critical for assessing risk of drug-induced QTc prolongation and potential for fatal cardiac arrhythmias such as torsades de pointes....

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Detalles Bibliográficos
Autores principales: Tehranchi, Ramin, Pettersson, Jonas, Melgaard, Anita E., Seitz, Friedeborg, Valeur, Anders, Maarbjerg, Stine Just
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026613/
https://www.ncbi.nlm.nih.gov/pubmed/35464292
http://dx.doi.org/10.1016/j.curtheres.2022.100668

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