Cargando…
Anti-Inflammatory and Neuroprotective Mechanisms of GTS-21, an α7 Nicotinic Acetylcholine Receptor Agonist, in Neuroinflammation and Parkinson’s Disease Mouse Models
Neuroinflammation is crucial in the progression of neurodegenerative diseases. Thus, controlling neuroinflammation has been proposed as an important therapeutic strategy for neurodegenerative disease. In the present study, we examined the anti-inflammatory and neuroprotective effects of GTS-21, a se...
Autores principales: | Park, Jung-Eun, Leem, Yea-Hyun, Park, Jin-Sun, Kim, Do-Yeon, Kang, Jihee Lee, Kim, Hee-Sun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026703/ https://www.ncbi.nlm.nih.gov/pubmed/35457238 http://dx.doi.org/10.3390/ijms23084420 |
Ejemplares similares
-
The selective α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates ventilator-induced inflammation and lung injury
por: Kox, M, et al.
Publicado: (2009) -
Effects of splenectomy and GTS-21, a selective α7 nicotinic acetylcholine receptor agonist, on the development of septic ileus in mice
por: Nullens, S, et al.
Publicado: (2014) -
Necrosulfonamide exerts neuroprotective effect by inhibiting necroptosis, neuroinflammation, and α-synuclein oligomerization in a subacute MPTP mouse model of Parkinson’s disease
por: Leem, Yea-Hyun, et al.
Publicado: (2023) -
The phosphodiesterase 10 inhibitor papaverine exerts anti-inflammatory and neuroprotective effects via the PKA signaling pathway in neuroinflammation and Parkinson’s disease mouse models
por: Lee, Yu-Young, et al.
Publicado: (2019) -
α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates DSS-induced intestinal colitis by improving intestinal mucosal barrier function
por: Ye, Ziping, et al.
Publicado: (2022)