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SFN Enhanced the Radiosensitivity of Cervical Cancer Cells via Activating LATS2 and Blocking Rad51/MDC1 Recruitment to DNA Damage Site

SIMPLE SUMMARY: Radiotherapy is the main treatment for cervical cancer patients in advanced stages. However a considerable number of patients are not sensitive to radiotherapy. Dysregulation of DNA double-strand break (DSB) repair is characteristic of cancer cells in a radiotherapy-resistance state....

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Detalles Bibliográficos
Autores principales: Wang, Shiyu, Wang, Yanan, Liu, Xiangnan, Yang, Yongbin, Wu, Sufang, Liu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026704/
https://www.ncbi.nlm.nih.gov/pubmed/35454780
http://dx.doi.org/10.3390/cancers14081872