Engineering a suite of E. coli strains for enhanced expression of bacterial polysaccharides and glycoconjugate vaccines

BACKGROUND: Glycoengineering, in the biotechnology workhorse bacterium, Escherichia coli, is a rapidly evolving field, particularly for the production of glycoconjugate vaccine candidates (bioconjugation). Efficient production of glycoconjugates requires the coordinated expression within the bacteri...

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Detalles Bibliográficos
Autores principales: Kay, Emily J., Mauri, Marta, Willcocks, Sam J., Scott, Timothy A., Cuccui, Jon, Wren, Brendan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026721/
https://www.ncbi.nlm.nih.gov/pubmed/35449016
http://dx.doi.org/10.1186/s12934-022-01792-7

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