Cargando…

Dissecting Tumor-Immune Microenvironment in Breast Cancer at a Spatial and Multiplex Resolution

SIMPLE SUMMARY: The evaluation of breast cancer immune microenvironment has been increasingly used in clinical practice, either by counting tumor infiltrating lymphocytes or assessing programmed death ligand 1 expression. However, the spatiotemporal organization of anti-breast cancer immune response...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tzoras, Evangelos, Zerdes, Ioannis, Tsiknakis, Nikos, Manikis, Georgios C., Mezheyeuski, Artur, Bergh, Jonas, Matikas, Alexios, Foukakis, Theodoros
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026731/ https://www.ncbi.nlm.nih.gov/pubmed/35454904 http://dx.doi.org/10.3390/cancers14081999

Ejemplares similares

Expression patterns and prognostic implications of tumor-infiltrating lymphocytes dynamics in early breast cancer patients receiving neoadjuvant therapy: A systematic review and meta-analysis
por: Zhu, Yajing, et al.
Publicado: (2022)

Beyond PD-1/PD-L1 Inhibition: What the Future Holds for Breast Cancer Immunotherapy
por: Chrétien, Sebastian, et al.
Publicado: (2019)

Genetic, transcriptional and post-translational regulation of the programmed death protein ligand 1 in cancer: biology and clinical correlations
por: Zerdes, Ioannis, et al.
Publicado: (2018)

The interplay between eosinophils and T cells in breast cancer immunotherapy
por: Zerdes, Ioannis, et al.
Publicado: (2023)

Discordance of PD-L1 Expression at the Protein and RNA Levels in Early Breast Cancer
por: Zerdes, Ioannis, et al.
Publicado: (2021)

PD-1 protein and gene expression as prognostic factors in early breast cancer
por: Matikas, Alexios, et al.
Publicado: (2020)

Programmed death‐ligand 1 gene expression is a prognostic marker in early breast cancer and provides additional prognostic value to 21‐gene and 70‐gene signatures in estrogen receptor‐positive disease
por: Zerdes, Ioannis, et al.
Publicado: (2020)

Interplay between copy number alterations and immune profiles in the early breast cancer Scandinavian Breast Group 2004-1 randomized phase II trial: results from a feasibility study
por: Zerdes, Ioannis, et al.
Publicado: (2021)

Women with short survival after diagnosis of metastatic breast cancer: a population-based registry study
por: Boman, Caroline, et al.
Publicado: (2022)

Chemotherapy use near the end-of-life in patients with metastatic breast cancer
por: Edman Kessler, Luisa, et al.
Publicado: (2020)

Immune gene expression and response to chemotherapy in advanced breast cancer
por: Foukakis, Theodoros, et al.
Publicado: (2018)

Harmonization Strategies in Multicenter MRI-Based Radiomics
por: Stamoulou, Elisavet, et al.
Publicado: (2022)

Avoiding over- and undertreatment in patients with resected node-positive breast cancer with the use of gene expression signatures: are we there yet?
por: Matikas, A, et al.
Publicado: (2019)

Dynamic evaluation of the immune infiltrate and immune function genes as predictive markers for neoadjuvant chemotherapy in hormone receptor positive, HER2 negative breast cancer
por: Matikas, Alexios, et al.
Publicado: (2018)

Long-term safety and survival outcomes from the Scandinavian Breast Group 2004-1 randomized phase II trial of tailored dose-dense adjuvant chemotherapy for early breast cancer
por: Matikas, Alexios, et al.
Publicado: (2017)

Pollen Grain Classification Based on Ensemble Transfer Learning on the Cretan Pollen Dataset
por: Tsiknakis, Nikos, et al.
Publicado: (2022)

STAT3 Activity Promotes Programmed-Death Ligand 1 Expression and Suppresses Immune Responses in Breast Cancer
por: Zerdes, Ioannis, et al.
Publicado: (2019)

Prognostic role of serum thymidine kinase 1 kinetics during neoadjuvant chemotherapy for early breast cancer
por: Matikas, A., et al.
Publicado: (2021)

Real World Evaluation of the Prosigna/PAM50 Test in a Node-Negative Postmenopausal Swedish Population: A Multicenter Study
por: Kjällquist, Una, et al.
Publicado: (2022)

Clinical instability of breast cancer markers is reflected in long-term in vitro estrogen deprivation studies
por: Milosevic, Jelena, et al.
Publicado: (2013)

Iatrogenic right coronary artery dissection distal to a total occlusion: a case report
por: Antoniades, Demetrios, et al.
Publicado: (2009)

Validation of a novel procedure for quantification of the formation of phosphoramide mustard by individuals treated with cyclophosphamide
por: von Stedingk, Hans, et al.
Publicado: (2014)

Multiplex Tissue Imaging: Spatial Revelations in the Tumor Microenvironment
por: van Dam, Stephanie, et al.
Publicado: (2022)

Long-term (up to 16 months) health-related quality of life after adjuvant tailored dose-dense chemotherapy vs. standard three-weekly chemotherapy in women with high-risk early breast cancer
por: Brandberg, Yvonne, et al.
Publicado: (2020)

The Tumor Microenvironment in Liver Metastases from Colorectal Carcinoma in the Context of the Histologic Growth Patterns
por: Garcia-Vicién, Gemma, et al.
Publicado: (2021)

Modeling Multiplexed Images with Spatial-LDA Reveals Novel Tissue Microenvironments
por: Chen, Zhenghao, et al.
Publicado: (2020)

Pre-Column Derivatization HPLC Procedure for the Quantitation of Aluminium Chlorohydrate in Antiperspirant Creams Using Quercetin as Chromogenic Reagent
por: Kalogria, Eleni, et al.
Publicado: (2014)

Immunotherapy in Hodgkin Lymphoma: Present Status and Future Strategies
por: Vassilakopoulos, Theodoros P., et al.
Publicado: (2019)

The Place of Targeted Agents in the Treatment of Elderly Patients with Metastatic Colorectal Cancer
por: Matikas, Alexios, et al.
Publicado: (2015)

Role of circulating free DNA in colorectal cancer
por: Matikas, Alexios, et al.
Publicado: (2016)

Expanded vacuum-stable gels for multiplexed high-resolution spatial histopathology
por: Bai, Yunhao, et al.
Publicado: (2023)

Explainable multiview framework for dissecting spatial relationships from highly multiplexed data
por: Tanevski, Jovan, et al.
Publicado: (2022)

Prolonged Complete Response in a Patient with Metastatic Pancreatic Adenocarcinoma after FOLFIRINOX Chemotherapy and Maintenance with FOLFIRI
por: Nikolaou, Christos, et al.
Publicado: (2015)

The promise and challenge of spatial omics in dissecting tumour microenvironment and the role of AI
por: Lee, Ren Yuan, et al.
Publicado: (2023)

Multiplex imaging reveals the architecture of the tumor immune microenvironment
por: Zhang, Junlei, et al.
Publicado: (2021)

2367: Defining critical features of the immune microenvironment in melanoma using multiplex immunohistochemistry and spatial analysis
por: Gartrell, Robyn, et al.
Publicado: (2018)

Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancer
por: Sandström Gerdtsson, Anna, et al.
Publicado: (2023)

Expression of insulin‐like growth factor‐1 receptor in circulating tumor cells of patients with breast cancer is associated with patient outcomes
por: Spiliotaki, Maria, et al.
Publicado: (2017)

Discordance of PIK3CA mutational status between primary and metastatic breast cancer: a systematic review and meta-analysis
por: Rosin, Justus, et al.
Publicado: (2023)

Highly Multiplexed Digital Spatial Profiling of the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma Patients
por: Kulasinghe, Arutha, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cqk8k96sk91ht4ge23kf47uand