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A Structural Perspective on Calprotectin as a Ligand of Receptors Mediating Inflammation and Potential Drug Target

Calprotectin, a heterodimer of S100A8 and S100A9 EF-hand calcium-binding proteins, is an integral part of the innate immune response. Calprotectin (CP) serves as a ligand for several pattern recognition cell surface receptors including the receptor for advanced glycation end products (RAGE), toll-li...

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Detalles Bibliográficos
Autores principales: Garcia, Velia, Perera, Yasiru Randika, Chazin, Walter Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026754/
https://www.ncbi.nlm.nih.gov/pubmed/35454108
http://dx.doi.org/10.3390/biom12040519

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