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Endothelial-Derived APT1-Mediated Macrophage-Endothelial Cell Interactions Participate in the Development of Atherosclerosis by Regulating the Ras/MAPK Signaling Pathway

Acyl-protein thioesterase 1 (APT1) can affect H-Ras localization and function by promoting its depalmitoylation. However, relatively little attention has been paid to the effects of APT1 on H-Ras in the cardiovascular system. In this study, we revealed its roles in atherosclerosis development using...

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Detalles Bibliográficos
Autores principales: Wang, Xinghua, Cheng, Lijun, Fu, Huaying, Chan, Calista Zhuo Yi, Tse, Gary, Liu, Tong, Li, Guangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026782/
https://www.ncbi.nlm.nih.gov/pubmed/35455042
http://dx.doi.org/10.3390/life12040551