Anti-Sm antibodies in the classification criteria of systemic lupus erythematosus

Systemic lupus erythematosus is characterized by autoantibodies and immune complex deposition. Several autoantibodies against mainly nuclear autoantigens have been described. One of these nuclear autoantigens is the Smith antigen. In this review, we focus on the position of autoantibodies against th...

Descripción completa

Detalles Bibliográficos
Autores principales: van Beers, Joyce J.B.C., Schreurs, Marco W.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
VSI:Autoantibodies in disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026971/
https://www.ncbi.nlm.nih.gov/pubmed/35464346
http://dx.doi.org/10.1016/j.jtauto.2022.100155
_version_ 1784691244465651712
author van Beers, Joyce J.B.C.
Schreurs, Marco W.J.
author_facet van Beers, Joyce J.B.C.
Schreurs, Marco W.J.
author_sort van Beers, Joyce J.B.C.
collection PubMed
description Systemic lupus erythematosus is characterized by autoantibodies and immune complex deposition. Several autoantibodies against mainly nuclear autoantigens have been described. One of these nuclear autoantigens is the Smith antigen. In this review, we focus on the position of autoantibodies against the Smith antigen in the classification criteria, the characteristics of the antigen, the production of anti-Smith antibodies in SLE and we discuss the different test methods available, together with their pitfalls, to detect these autoantibodies.
format Online
Article
Text
id pubmed-9026971
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-90269712022-04-23 Anti-Sm antibodies in the classification criteria of systemic lupus erythematosus van Beers, Joyce J.B.C. Schreurs, Marco W.J. J Transl Autoimmun VSI:Autoantibodies in disease Systemic lupus erythematosus is characterized by autoantibodies and immune complex deposition. Several autoantibodies against mainly nuclear autoantigens have been described. One of these nuclear autoantigens is the Smith antigen. In this review, we focus on the position of autoantibodies against the Smith antigen in the classification criteria, the characteristics of the antigen, the production of anti-Smith antibodies in SLE and we discuss the different test methods available, together with their pitfalls, to detect these autoantibodies. Elsevier 2022-04-13 /pmc/articles/PMC9026971/ /pubmed/35464346 http://dx.doi.org/10.1016/j.jtauto.2022.100155 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle VSI:Autoantibodies in disease
van Beers, Joyce J.B.C.
Schreurs, Marco W.J.
Anti-Sm antibodies in the classification criteria of systemic lupus erythematosus
title Anti-Sm antibodies in the classification criteria of systemic lupus erythematosus
title_full Anti-Sm antibodies in the classification criteria of systemic lupus erythematosus
title_fullStr Anti-Sm antibodies in the classification criteria of systemic lupus erythematosus
title_full_unstemmed Anti-Sm antibodies in the classification criteria of systemic lupus erythematosus
title_short Anti-Sm antibodies in the classification criteria of systemic lupus erythematosus
title_sort anti-sm antibodies in the classification criteria of systemic lupus erythematosus
topic VSI:Autoantibodies in disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026971/
https://www.ncbi.nlm.nih.gov/pubmed/35464346
http://dx.doi.org/10.1016/j.jtauto.2022.100155
work_keys_str_mv AT vanbeersjoycejbc antismantibodiesintheclassificationcriteriaofsystemiclupuserythematosus
AT schreursmarcowj antismantibodiesintheclassificationcriteriaofsystemiclupuserythematosus

Ejemplares similares