Cargando…

Rutaecarpine Promotes Adipose Thermogenesis and Protects against HFD-Induced Obesity via AMPK/PGC-1α Pathway

Pharmacological activation of adaptive thermogenesis to increase energy expenditure is considered to be a novel strategy for obesity. Peroxisome-proliferator-activated receptor γ co-activator-1α (PGC-1α), which serves as an inducible co-activator in energy expenditure, is highly expressed in brown a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Dandan, Duan, Yanan, Yu, Shuxiang, Zhang, Xinwen, Li, Ni, Li, Jingya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027001/ https://www.ncbi.nlm.nih.gov/pubmed/35455466 http://dx.doi.org/10.3390/ph15040469

Ejemplares similares

D-allulose ameliorates adiposity through the AMPK-SIRT1-PGC-1α pathway in HFD-induced SD rats
por: Lee, Geum-Hwa, et al.
Publicado: (2021)

AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue
por: Wu, Lingyan, et al.
Publicado: (2018)

An emerging role for epigenetic regulation of Pgc-1α expression in environmentally stimulated brown adipose thermogenesis
por: Gill, J.A., et al.
Publicado: (2017)

Calebin-A prevents HFD-induced obesity in mice by promoting thermogenesis and modulating gut microbiota
por: Lee, Pei-Sheng, et al.
Publicado: (2022)

Selegiline Modulates Lipid Metabolism by Activating AMPK Pathways of Epididymal White Adipose Tissues in HFD-Fed Obese Mice
por: Joung, Hye-Young, et al.
Publicado: (2023)

Adipose tissue-specific ablation of PGC-1β impairs thermogenesis in brown fat
por: Funda, Jiří, et al.
Publicado: (2022)

NT-PGC-1α Activation Attenuates High-Fat Diet–Induced Obesity by Enhancing Brown Fat Thermogenesis and Adipose Tissue Oxidative Metabolism
por: Jun, Hee-Jin, et al.
Publicado: (2014)

Sodium nitroprusside protects HFD induced gut dysfunction via activating AMPKα/SIRT1 signaling
por: Li, Xiaomei, et al.
Publicado: (2021)

Estradiol Regulates Brown Adipose Tissue Thermogenesis via Hypothalamic AMPK
por: Martínez de Morentin, Pablo B., et al.
Publicado: (2014)

A PGC1α-dependent myokine that drives browning of white fat and thermogenesis
por: Boström, Pontus, et al.
Publicado: (2012)

Endothelial AMPKα1/PRKAA1 exacerbates inflammation in HFD‐fed mice
por: Yang, Qiuhua, et al.
Publicado: (2021)

AMPK activation protects against diet induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue
por: Pollard, Alice E., et al.
Publicado: (2019)

Progress in the Studies on Rutaecarpine
por: Lee, Seung Ho, et al.
Publicado: (2008)

Protein Kinase SGK2 Is Induced by the β(3) Adrenergic Receptor-cAMP-PKA-PGC-1α/NT-PGC-1α Axis but Dispensable for Brown/Beige Adipose Tissue Thermogenesis
por: Park, Chul-Hong, et al.
Publicado: (2021)

Distinct AMPK-Mediated FAS/HSL Pathway Is Implicated in the Alleviating Effect of Nuciferine on Obesity and Hepatic Steatosis in HFD-Fed Mice
por: Xu, Hanyuan, et al.
Publicado: (2022)

Electrical Neurostimulation Promotes Brown Adipose Tissue Thermogenesis
por: Li, Zhuang, et al.
Publicado: (2020)

Zinc-α2-Glycoprotein Is Associated with Obesity in Chinese People and HFD-Induced Obese Mice
por: Liu, Meijuan, et al.
Publicado: (2018)

Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1α/ERRα
por: Yan, Ming, et al.
Publicado: (2016)

Promising derivatives of rutaecarpine with diverse pharmacological activities
por: Li, Deping, et al.
Publicado: (2023)

Pharmacological Effects of Rutaecarpine as a Cardiovascular Protective Agent
por: Jia, Sujie, et al.
Publicado: (2010)

Kdm2a deficiency in macrophages enhances thermogenesis to protect mice against HFD-induced obesity by enhancing H3K36me2 at the Pparg locus
por: Chen, Longmin, et al.
Publicado: (2021)

In Vivo Correction of COX Deficiency by Activation of the AMPK/PGC-1α Axis
por: Viscomi, Carlo, et al.
Publicado: (2011)

Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning
por: Patil, Mallikarjun, et al.
Publicado: (2017)

MANF in POMC Neurons Promotes Brown Adipose Tissue Thermogenesis and Protects Against Diet-Induced Obesity
por: Tang, Qin, et al.
Publicado: (2022)

MicroRNAs as Mediators of Adipose Thermogenesis and Potential Therapeutic Targets for Obesity
por: Ma, Lunkun, et al.
Publicado: (2022)

Low-protein/high-carbohydrate diet induces AMPK-dependent canonical and non-canonical thermogenesis in subcutaneous adipose tissue
por: Aquilano, Katia, et al.
Publicado: (2020)

A map of the PGC-1α- and NT-PGC-1α-regulated transcriptional network in brown adipose tissue
por: Chang, Ji Suk, et al.
Publicado: (2018)

Phytohemagglutinin ameliorates HFD-induced obesity by increasing energy expenditure
por: Zhang, Yunxia, et al.
Publicado: (2021)

Berberine modulates deacetylation of PPARγ to promote adipose tissue remodeling and thermogenesis via AMPK/SIRT1 pathway
por: Xu, Yingxi, et al.
Publicado: (2021)

Time effect of rutaecarpine on caffeine pharmacokinetics in rats
por: Estari, Rohit Kumar, et al.
Publicado: (2021)

Time since menopause and skeletal muscle estrogen receptors, PGC-1α, and AMPK
por: Park, Young-Min, et al.
Publicado: (2017)

MiR-494-3p regulates mitochondrial biogenesis and thermogenesis through PGC1-α signalling in beige adipocytes
por: Lemecha, Mengistu, et al.
Publicado: (2018)

Contribution of PGC-1α to Obesity- and Caloric Restriction-Related Physiological Changes in White Adipose Tissue
por: Kobayashi, Masaki, et al.
Publicado: (2021)

Maternal Exercise Mediates Hepatic Metabolic Programming via Activation of AMPK-PGC1α Axis in the Offspring of Obese Mothers
por: Kasper, Philipp, et al.
Publicado: (2021)

AMPK in the Ventromedial Nucleus of the Hypothalamus: A Key Regulator for Thermogenesis
por: Liu, Hailan, et al.
Publicado: (2020)

Bitter Orange (Citrus aurantium Linné) Improves Obesity by Regulating Adipogenesis and Thermogenesis through AMPK Activation
por: Park, Jinbong, et al.
Publicado: (2019)

Translational issues in targeting brown adipose tissue thermogenesis for human obesity management
por: Dulloo, Abdul G
Publicado: (2013)

Anti-obesity activity of OBEX is regulated by activation of thermogenesis and decreasing adiposity gain
por: Carreira, Marcos C., et al.
Publicado: (2018)

Facultative protein selenation regulates redox sensitivity, adipose tissue thermogenesis, and obesity
por: Jedrychowski, Mark P., et al.
Publicado: (2020)

Diet Control and Swimming Exercise Ameliorate HFD-Induced Cognitive Impairment Related to the SIRT1-NF-κB/PGC-1α Pathways in ApoE-/- Mice
por: Wei, Wei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_39p5ko6ejv07drhctuklgnr7e7