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Deuterated Arachidonic Acid Ameliorates Lipopolysaccharide-Induced Lung Damage in Mice

Arachidonic acid (ARA) is a major component of lipid bilayers as well as the key substrate for the eicosanoid cascades. ARA is readily oxidized, and its non-enzymatic and enzymatic oxidation products induce inflammatory responses in nearly all tissues, including lung tissues. Deuteration at bis-ally...

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Detalles Bibliográficos
Autores principales: Molchanova, Alla Y., Rjabceva, Svetlana N., Melik-Kasumov, Tigran B., Pestov, Nikolay B., Angelova, Plamena R., Shmanai, Vadim V., Sharko, Olga L., Bekish, Andrei V., James, Genevieve, Park, Hui Gyu, Udalova, Irina A., Brenna, J. Thomas, Shchepinov, Mikhail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027010/
https://www.ncbi.nlm.nih.gov/pubmed/35453366
http://dx.doi.org/10.3390/antiox11040681