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Tau Protein Modulates Perineuronal Extracellular Matrix Expression in the TauP301L-acan Mouse Model

Tau mutations promote the formation of tau oligomers and filaments, which are neuropathological signs of several tau-associated dementias. Types of neurons in the CNS are spared of tau pathology and are surrounded by a specialized form of extracellular matrix; called perineuronal nets (PNs). Aggreca...

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Detalles Bibliográficos
Autores principales: Schmidt, Sophie, Holzer, Max, Arendt, Thomas, Sonntag, Mandy, Morawski, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027016/
https://www.ncbi.nlm.nih.gov/pubmed/35454094
http://dx.doi.org/10.3390/biom12040505