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Backbone NMR assignments of the extensive human and chicken TRPV4 N-terminal intrinsically disordered regions as important players in ion channel regulation

Transient receptor potential (TRP) channels are important pharmacological targets due to their ability to act as sensory transducers on the organismic and cellular level, as polymodal signal integrators and because of their role in numerous diseases. However, a detailed molecular understanding of th...

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Detalles Bibliográficos
Autores principales: Goretzki, Benedikt, Tebbe, Frederike, Mitrovic, Sarah-Ana, Hellmich, Ute A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027025/
https://www.ncbi.nlm.nih.gov/pubmed/35451798
http://dx.doi.org/10.1007/s12104-022-10080-9