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PEDF is an antifibrosis factor that inhibits the activation of fibroblasts in a bleomycin-induced pulmonary fibrosis rat model

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a highly heterogeneous and fatal lung disease. In addition to dense fibrous tissue, abnormal angiogenesis is also an important feature of IPF. Pigment epithelium-derived factor (PEDF) is an angiogenesis inhibitor and a potential anti-fibrous factor....

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Detalles Bibliográficos
Autores principales: Qin, Xichun, Jia, Caili, Liang, Jingtian, Chen, Jiali, Liu, Xiucheng, Chao, Zhixiang, Qin, Hao, Yuan, Yanliang, Liu, Zhiwei, Zhang, Zhongming, Dong, Hongyan, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027047/
https://www.ncbi.nlm.nih.gov/pubmed/35459189
http://dx.doi.org/10.1186/s12931-022-02027-4