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Dual PI3K/Akt Inhibitors Bearing Coumarin-Thiazolidine Pharmacophores as Potential Apoptosis Inducers in MCF-7 Cells

Breast cancer is the most common malignancy worldwide; therefore, the development of new anticancer agents is essential for improved tumor control. By adopting the pharmacophore hybridization approach, two series of 7-hydroxyl-4-methylcoumarin hybridized with thiosemicarbazone (V–VI) and thiazolidin...

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Detalles Bibliográficos
Autores principales:	Abdelnaby, Rana M., Rateb, Heba S., Ali, Omaima, Saad, Ahmed S., Nadeem, Rania I., Abou-Seri, Sahar M., Amin, Kamilia M., Younis, Nancy S., Abdelhady, Rasha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027131/ https://www.ncbi.nlm.nih.gov/pubmed/35455425 http://dx.doi.org/10.3390/ph15040428

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