Cargando…

Cardiovascular Characteristics of Zucker Fatty Diabetes Mellitus Rats, an Animal Model for Obesity and Type 2 Diabetes

Zucker fatty diabetes mellitus (ZFDM) rats harboring the missense mutation (fa) in a leptin receptor gene have been recently established as a novel animal model of obesity and type 2 diabetes (T2D). Here, we explored changes in cardiovascular dynamics including blood pressure and heart rate (HR) ass...

Descripción completa

Detalles Bibliográficos
Autores principales:	Otani, Kosuke, Funada, Hiroshi, Teranishi, Risa, Okada, Muneyoshi, Yamawaki, Hideyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027163/ https://www.ncbi.nlm.nih.gov/pubmed/35457048 http://dx.doi.org/10.3390/ijms23084228

Ejemplares similares

Diverse distribution of tyrosine receptor kinase B isoforms in rat multiple tissues
por: OTANI, Kosuke, et al.
Publicado: (2017)

Plasma small extracellular vesicles in hypertensive rats impair reactivity of isolated blood vessels
por: FUJIOKA, Yusei, et al.
Publicado: (2020)

Optimal Isolation Method of Small Extracellular Vesicles from Rat Plasma
por: Otani, Kosuke, et al.
Publicado: (2019)

Age-dependent increase in activity of eukaryotic elongation factor 2 kinase in mesenteric arteries from spontaneously hypertensive rats
por: KODAMA, Tomoko, et al.
Publicado: (2020)

Chemokine-like Receptor 1 in Brain of Spontaneously Hypertensive Rats Mediates Systemic Hypertension
por: Yamamoto, Atsunori, et al.
Publicado: (2021)

Coenzyme A and Its Thioester Pools in Obese Zucker and Zucker Diabetic Fatty Rats
por: Chohnan, Shigeru, et al.
Publicado: (2020)

Decreased Expression of Canstatin in Rat Model of Monocrotaline-Induced Pulmonary Arterial Hypertension: Protective Effect of Canstatin on Right Ventricular Remodeling
por: Sugiyama, Akira, et al.
Publicado: (2020)

Small extracellular vesicles from rat plasma promote migration and proliferation of vascular smooth muscle cells
por: OTANI, Kosuke, et al.
Publicado: (2020)

Preventive Effect of Canstatin against Ventricular Arrhythmia Induced by Ischemia/Reperfusion Injury: A Pilot Study
por: Sugiyama, Akira, et al.
Publicado: (2021)

A single injection of periostin decreases cardiac voltage-gated Na(+) channel in rat ventricles
por: IMOTO, Keisuke, et al.
Publicado: (2021)

Chemerin fragments show different effects on systemic blood pressure dependent on carboxyl-terminal cleavage site
por: YAMAMOTO, Atsunori, et al.
Publicado: (2022)

Autocrine role of senescent cardiac fibroblasts-derived extracellular vesicles
por: FUJIOKA, Yusei, et al.
Publicado: (2023)

Anti-Obesity Effects of Onion Extract in Zucker Diabetic Fatty Rats
por: Yoshinari, Orie, et al.
Publicado: (2012)

Dynamic Development of Fecal Microbiome During the Progression of Diabetes Mellitus in Zucker Diabetic Fatty Rats
por: Zhou, Wen, et al.
Publicado: (2019)

Expression of fourteen novel obesity-related genes in zucker diabetic fatty rats
por: Schmid, Peter M, et al.
Publicado: (2012)

A Novel Rat Model of Type 2 Diabetes: The Zucker Fatty Diabetes Mellitus ZFDM Rat
por: Yokoi, Norihide, et al.
Publicado: (2013)

Influence of diabetes mellitus duration on the efficacy of ischemic preconditioning in a Zucker diabetic fatty rat model
por: Hjortbak, Marie Vognstoft, et al.
Publicado: (2018)

Variability in Zucker diabetic fatty rats: differences in disease progression in hyperglycemic and normoglycemic animals
por: Wang, Xi, et al.
Publicado: (2014)

Human Omentin-1 Administration Ameliorates Hypertensive Complications without Affecting Hypertension in Spontaneously Hypertensive Rats
por: Okamura, Yuta, et al.
Publicado: (2023)

Reduction in the Dietary VA Status Prevents Type 2 Diabetes and Obesity in Zucker Diabetic Fatty Rats
por: Wang, Tiannan, et al.
Publicado: (2022)

Hepatic Transcriptome Analysis Revealing the Molecular Pathogenesis of Type 2 Diabetes Mellitus in Zucker Diabetic Fatty Rats
por: Xia, Chengdong, et al.
Publicado: (2020)

Diabetic cardiomyopathy in Zucker diabetic fatty rats: the forgotten right ventricle
por: van den Brom, Charissa E, et al.
Publicado: (2010)

Cognitive Performance during the Development of Diabetes in the Zucker Diabetic Fatty Rat
por: Spoelder, Marcia, et al.
Publicado: (2023)

Diabetic Nephropathy Amelioration by a Low-Dose Sitagliptin in an Animal Model of Type 2 Diabetes (Zucker Diabetic Fatty Rat)
por: Mega, Cristina, et al.
Publicado: (2011)

Urinary Metabolomic Profiling in Zucker Diabetic Fatty Rats with Type 2 Diabetes Mellitus Treated with Glimepiride, Metformin, and Their Combination
por: Dong, Yu, et al.
Publicado: (2016)

Histological Evaluation of Diabetic Neurodegeneration in the Retina of Zucker Diabetic Fatty (ZDF) Rats
por: Szabó, Klaudia, et al.
Publicado: (2017)

Elevated pulmonary arterial pressure in Zucker diabetic fatty rats
por: Morales-Cano, Daniel, et al.
Publicado: (2019)

Effect of KIOM-79 on Diabetes-Induced Myocardial Fibrosis in Zucker Diabetic Fatty Rats
por: Kim, Junghyun, et al.
Publicado: (2013)

Preventive effects of Morus alba L. anthocyanins on diabetes in Zucker diabetic fatty rats
por: SARIKAPHUTI, ARIYA, et al.
Publicado: (2013)

Long-term treatment with metformin in the prevention of fatty liver in Zucker diabetic fatty rats
por: Sui, Yi, et al.
Publicado: (2019)

Mechanisms Underlying a Decrease in KCl-Induced Contraction after Long-Term Serum-Free Organ Culture of Rat Isolated Mesenteric Artery
por: MORITA, Tomoka, et al.
Publicado: (2014)

Endostatin inhibits T-type Ca(2+) channel current in guinea pig ventricular myocyte
por: YASUDA, Jumpei, et al.
Publicado: (2015)

Periostin Mediates Right Ventricular Failure through Induction of Inducible Nitric Oxide Synthase Expression in Right Ventricular Fibroblasts from Monocrotaline-Induced Pulmonary Arterial Hypertensive Rats
por: Imoto, Keisuke, et al.
Publicado: (2018)

Eukaryotic elongation factor 2 kinase inhibitor, A484954 inhibits noradrenaline-induced acute increase of blood pressure in rats
por: KODAMA, Tomoko, et al.
Publicado: (2018)

Expression profile of matricellular proteins in hypertrophied right ventricle of monocrotaline-induced pulmonary hypertensive rats
por: IMOTO, Keisuke, et al.
Publicado: (2017)

Eukaryotic elongation factor 2 kinase inhibitor, A484954 potentiates β-adrenergic receptor agonist-induced acute decrease in diastolic blood pressure in rats
por: KODAMA, Tomoko, et al.
Publicado: (2019)

Cardiovascular disease progression in female Zucker Diabetic Fatty rats occurs via unique mechanisms compared to males
por: Lum-Naihe, Kelly, et al.
Publicado: (2017)

Effects of Alpha-Lipoic Acid on Oxidative Stress and Kinin Receptor Expression in Obese Zucker Diabetic Fatty Rats
por: Midaoui, Adil El, et al.
Publicado: (2015)

Dose-Dependent Effect of Melatonin on BAT Thermogenesis in Zücker Diabetic Fatty Rat: Future Clinical Implications for Obesity
por: Aouichat, Samira, et al.
Publicado: (2022)

Melatonin Improves Mitochondrial Dynamics and Function in the Kidney of Zücker Diabetic Fatty Rats
por: Agil, Ahmad, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hdrg2f74eoc6kna2s9ve40v7g9