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Crystal structure of SARS-CoV 3C-like protease with baicalein

The 3C-like protease (M(pro), 3CL(pro)) plays a key role in the replication process in coronaviruses (CoVs). The M(pro) is an essential enzyme mediates CoVs replication and is a promising target for development of antiviral drugs. Until now, baicalein has been shown the specific activity for SARS-Co...

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Detalles Bibliográficos
Autores principales:	Feng, Jingwen, Li, Dongyang, Zhang, Jin, Yin, Xiushan, Li, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027212/ https://www.ncbi.nlm.nih.gov/pubmed/35490659 http://dx.doi.org/10.1016/j.bbrc.2022.04.086

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