Influence of Experimental End Point on the Therapeutic Efficacy of Essential and Additional Antidotes in Organophosphorus Nerve Agent-Intoxicated Mice

The therapeutic efficacy of treatments for acute intoxication with highly toxic organophosphorus compounds, called nerve agents, usually involves determination of LD(50) values 24 h after nerve agent challenge without and with a single administration of the treatment. Herein, the LD(50) values of fo...

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Detalles Bibliográficos
Autores principales: Kassa, Jiri, Timperley, Christopher M., Bird, Mike, Green, A. Christopher, Tattersall, John E. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027337/
https://www.ncbi.nlm.nih.gov/pubmed/35448453
http://dx.doi.org/10.3390/toxics10040192

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