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Onychomycosis Caused by Fusarium Species

Onychomycosis is a nail fungal infection that produces nail discolouration, thickness, and separation from the nail bed. The species of the Fusarium genus that cause onychomycosis are emerging and the number of cases has increased throughout the years. Microscopic examination, as well as cultures, a...

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Autores principales: Uemura, Eduardo Vinicius Grego, Barbosa, Marcelo dos Santos, Simionatto, Simone, Al-Harrasi, Ahmed, Al-Hatmi, Abdullah M. S., Rossato, Luana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027400/
https://www.ncbi.nlm.nih.gov/pubmed/35448591
http://dx.doi.org/10.3390/jof8040360
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author Uemura, Eduardo Vinicius Grego
Barbosa, Marcelo dos Santos
Simionatto, Simone
Al-Harrasi, Ahmed
Al-Hatmi, Abdullah M. S.
Rossato, Luana
author_facet Uemura, Eduardo Vinicius Grego
Barbosa, Marcelo dos Santos
Simionatto, Simone
Al-Harrasi, Ahmed
Al-Hatmi, Abdullah M. S.
Rossato, Luana
author_sort Uemura, Eduardo Vinicius Grego
collection PubMed
description Onychomycosis is a nail fungal infection that produces nail discolouration, thickness, and separation from the nail bed. The species of the Fusarium genus that cause onychomycosis are emerging and the number of cases has increased throughout the years. Microscopic examination, as well as cultures, are required for the accurate diagnosis of onychomycosis. The goal of treatment is to eliminate the organism that causes the disease and restore the nail’s normal appearance. Here, we provide an overview of the onychomycosis cases that have been reported in literature over the last 24 years, which have been caused by the Fusarium species. We performed a review on the onychomycosis cases caused by the Fusarium species from January 1997 to January 2021. Patients aged between 40 and 49 years made up 30.23% of the cases. The most common aetiologic species was Fusarium solani species complex (FSSC), which accounted for 44.11% of the cases, followed by F. fujikuroi species complex (FFSC), which accounted for 17.64%; 14.70% of the cases were due to F. dimerum species complex (FDSC) and 14.70% of the cases were due F. oxysporum species complex (FOSC). Europe accounted for 29.06% of the cases caused by FOSC, whereas Africa accounted for 46.67% of the cases due to FSSC. The clinical presentation of onychomycosis due to Fusarium spp. is commonly the distal–lateral pattern of onychomycosis. Identification of the infectious agent in onychomycosis cases due to Fusarium is crucial in deciding the proper treatment. Although antifungal susceptibility tests have only been performed in a few cases, susceptibility testing can help with patient management.
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spelling pubmed-90274002022-04-23 Onychomycosis Caused by Fusarium Species Uemura, Eduardo Vinicius Grego Barbosa, Marcelo dos Santos Simionatto, Simone Al-Harrasi, Ahmed Al-Hatmi, Abdullah M. S. Rossato, Luana J Fungi (Basel) Review Onychomycosis is a nail fungal infection that produces nail discolouration, thickness, and separation from the nail bed. The species of the Fusarium genus that cause onychomycosis are emerging and the number of cases has increased throughout the years. Microscopic examination, as well as cultures, are required for the accurate diagnosis of onychomycosis. The goal of treatment is to eliminate the organism that causes the disease and restore the nail’s normal appearance. Here, we provide an overview of the onychomycosis cases that have been reported in literature over the last 24 years, which have been caused by the Fusarium species. We performed a review on the onychomycosis cases caused by the Fusarium species from January 1997 to January 2021. Patients aged between 40 and 49 years made up 30.23% of the cases. The most common aetiologic species was Fusarium solani species complex (FSSC), which accounted for 44.11% of the cases, followed by F. fujikuroi species complex (FFSC), which accounted for 17.64%; 14.70% of the cases were due to F. dimerum species complex (FDSC) and 14.70% of the cases were due F. oxysporum species complex (FOSC). Europe accounted for 29.06% of the cases caused by FOSC, whereas Africa accounted for 46.67% of the cases due to FSSC. The clinical presentation of onychomycosis due to Fusarium spp. is commonly the distal–lateral pattern of onychomycosis. Identification of the infectious agent in onychomycosis cases due to Fusarium is crucial in deciding the proper treatment. Although antifungal susceptibility tests have only been performed in a few cases, susceptibility testing can help with patient management. MDPI 2022-03-31 /pmc/articles/PMC9027400/ /pubmed/35448591 http://dx.doi.org/10.3390/jof8040360 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Uemura, Eduardo Vinicius Grego
Barbosa, Marcelo dos Santos
Simionatto, Simone
Al-Harrasi, Ahmed
Al-Hatmi, Abdullah M. S.
Rossato, Luana
Onychomycosis Caused by Fusarium Species
title Onychomycosis Caused by Fusarium Species
title_full Onychomycosis Caused by Fusarium Species
title_fullStr Onychomycosis Caused by Fusarium Species
title_full_unstemmed Onychomycosis Caused by Fusarium Species
title_short Onychomycosis Caused by Fusarium Species
title_sort onychomycosis caused by fusarium species
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027400/
https://www.ncbi.nlm.nih.gov/pubmed/35448591
http://dx.doi.org/10.3390/jof8040360
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