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Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease
Adult-onset Still’s disease is a complex autoinflammatory disease with a multifactorial etiology. Its presentation is less stereotypical than that of a monogenic autoinflammatory disease and is actually relatively common with few specific signs. To avoid under- or over-prescription of complementary...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027491/ https://www.ncbi.nlm.nih.gov/pubmed/35456325 http://dx.doi.org/10.3390/jcm11082232 |
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author | Poursac, Nicolas Odriozola, Itsaso Truchetet, Marie-Elise |
author_facet | Poursac, Nicolas Odriozola, Itsaso Truchetet, Marie-Elise |
author_sort | Poursac, Nicolas |
collection | PubMed |
description | Adult-onset Still’s disease is a complex autoinflammatory disease with a multifactorial etiology. Its presentation is less stereotypical than that of a monogenic autoinflammatory disease and is actually relatively common with few specific signs. To avoid under- or over-prescription of complementary examinations, it is useful to advance in a structured manner, taking into consideration the actual added value of each supplemental examination. In this review, we detail the different complementary tests used in adult Still’s disease. We consider them from three different angles: positive diagnostic approach, the differential diagnosis, and the screening for complications of the disease. After discussing the various tests at our disposal, we look at the classical diagnostic strategy in order to propose a structured algorithm that can be used in clinical practice. We conclude with the prospects of new complementary examinations, which could in the future modify the management of patients. |
format | Online Article Text |
id | pubmed-9027491 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-90274912022-04-23 Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease Poursac, Nicolas Odriozola, Itsaso Truchetet, Marie-Elise J Clin Med Review Adult-onset Still’s disease is a complex autoinflammatory disease with a multifactorial etiology. Its presentation is less stereotypical than that of a monogenic autoinflammatory disease and is actually relatively common with few specific signs. To avoid under- or over-prescription of complementary examinations, it is useful to advance in a structured manner, taking into consideration the actual added value of each supplemental examination. In this review, we detail the different complementary tests used in adult Still’s disease. We consider them from three different angles: positive diagnostic approach, the differential diagnosis, and the screening for complications of the disease. After discussing the various tests at our disposal, we look at the classical diagnostic strategy in order to propose a structured algorithm that can be used in clinical practice. We conclude with the prospects of new complementary examinations, which could in the future modify the management of patients. MDPI 2022-04-16 /pmc/articles/PMC9027491/ /pubmed/35456325 http://dx.doi.org/10.3390/jcm11082232 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Poursac, Nicolas Odriozola, Itsaso Truchetet, Marie-Elise Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease |
title | Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease |
title_full | Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease |
title_fullStr | Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease |
title_full_unstemmed | Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease |
title_short | Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease |
title_sort | strategy and challenges of paraclinical examinations in adult-onset still’s disease |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027491/ https://www.ncbi.nlm.nih.gov/pubmed/35456325 http://dx.doi.org/10.3390/jcm11082232 |
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