Preparation of Polyvinylidene Fluoride–Gold Nanoparticles Electrospinning Nanofiber Membranes

In this work, gold nanoparticles (AuNPs) and curcumin drug were incorporated in polyvinylidene fluoride (PVDF) nanofibers by electrospinning as a novel tissue engineering scaffold in nerve regeneration. The influence of AuNPs on the morphology, crystallinity, and drug release behavior of nanofiber m...

Descripción completa

Detalles Bibliográficos
Autores principales: Ge, Xuemei, Wu, Shang, Shen, Wen, Chen, Lijuan, Zheng, Yan, Ao, Fen, Ning, Yuanlan, Mao, Yueyang, Chen, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027547/
https://www.ncbi.nlm.nih.gov/pubmed/35447690
http://dx.doi.org/10.3390/bioengineering9040130
Descripción
Sumario:In this work, gold nanoparticles (AuNPs) and curcumin drug were incorporated in polyvinylidene fluoride (PVDF) nanofibers by electrospinning as a novel tissue engineering scaffold in nerve regeneration. The influence of AuNPs on the morphology, crystallinity, and drug release behavior of nanofiber membranes was characterized. A successful composite nanofiber membrane sample was observed by scanning electron microscopy (SEM). The addition of AuNPs showed the improved as well as prolonged cumulative release of the drug. The results indicated that PVDF–AuNPs nanofiber membrane could potentially be applied for nerve regeneration.

Ejemplares similares