Preparation of Polyvinylidene Fluoride–Gold Nanoparticles Electrospinning Nanofiber Membranes

In this work, gold nanoparticles (AuNPs) and curcumin drug were incorporated in polyvinylidene fluoride (PVDF) nanofibers by electrospinning as a novel tissue engineering scaffold in nerve regeneration. The influence of AuNPs on the morphology, crystallinity, and drug release behavior of nanofiber m...

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Detalles Bibliográficos
Autores principales: Ge, Xuemei, Wu, Shang, Shen, Wen, Chen, Lijuan, Zheng, Yan, Ao, Fen, Ning, Yuanlan, Mao, Yueyang, Chen, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027547/
https://www.ncbi.nlm.nih.gov/pubmed/35447690
http://dx.doi.org/10.3390/bioengineering9040130
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author Ge, Xuemei
Wu, Shang
Shen, Wen
Chen, Lijuan
Zheng, Yan
Ao, Fen
Ning, Yuanlan
Mao, Yueyang
Chen, Zhong
author_facet Ge, Xuemei
Wu, Shang
Shen, Wen
Chen, Lijuan
Zheng, Yan
Ao, Fen
Ning, Yuanlan
Mao, Yueyang
Chen, Zhong
author_sort Ge, Xuemei
collection PubMed
description In this work, gold nanoparticles (AuNPs) and curcumin drug were incorporated in polyvinylidene fluoride (PVDF) nanofibers by electrospinning as a novel tissue engineering scaffold in nerve regeneration. The influence of AuNPs on the morphology, crystallinity, and drug release behavior of nanofiber membranes was characterized. A successful composite nanofiber membrane sample was observed by scanning electron microscopy (SEM). The addition of AuNPs showed the improved as well as prolonged cumulative release of the drug. The results indicated that PVDF–AuNPs nanofiber membrane could potentially be applied for nerve regeneration.
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spelling pubmed-90275472022-04-23 Preparation of Polyvinylidene Fluoride–Gold Nanoparticles Electrospinning Nanofiber Membranes Ge, Xuemei Wu, Shang Shen, Wen Chen, Lijuan Zheng, Yan Ao, Fen Ning, Yuanlan Mao, Yueyang Chen, Zhong Bioengineering (Basel) Article In this work, gold nanoparticles (AuNPs) and curcumin drug were incorporated in polyvinylidene fluoride (PVDF) nanofibers by electrospinning as a novel tissue engineering scaffold in nerve regeneration. The influence of AuNPs on the morphology, crystallinity, and drug release behavior of nanofiber membranes was characterized. A successful composite nanofiber membrane sample was observed by scanning electron microscopy (SEM). The addition of AuNPs showed the improved as well as prolonged cumulative release of the drug. The results indicated that PVDF–AuNPs nanofiber membrane could potentially be applied for nerve regeneration. MDPI 2022-03-24 /pmc/articles/PMC9027547/ /pubmed/35447690 http://dx.doi.org/10.3390/bioengineering9040130 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ge, Xuemei
Wu, Shang
Shen, Wen
Chen, Lijuan
Zheng, Yan
Ao, Fen
Ning, Yuanlan
Mao, Yueyang
Chen, Zhong
Preparation of Polyvinylidene Fluoride–Gold Nanoparticles Electrospinning Nanofiber Membranes
title Preparation of Polyvinylidene Fluoride–Gold Nanoparticles Electrospinning Nanofiber Membranes
title_full Preparation of Polyvinylidene Fluoride–Gold Nanoparticles Electrospinning Nanofiber Membranes
title_fullStr Preparation of Polyvinylidene Fluoride–Gold Nanoparticles Electrospinning Nanofiber Membranes
title_full_unstemmed Preparation of Polyvinylidene Fluoride–Gold Nanoparticles Electrospinning Nanofiber Membranes
title_short Preparation of Polyvinylidene Fluoride–Gold Nanoparticles Electrospinning Nanofiber Membranes
title_sort preparation of polyvinylidene fluoride–gold nanoparticles electrospinning nanofiber membranes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027547/
https://www.ncbi.nlm.nih.gov/pubmed/35447690
http://dx.doi.org/10.3390/bioengineering9040130
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