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Neuroprotective Effects of PARP Inhibitors in Drosophila Models of Alzheimer’s Disease

Alzheimer’s disease (AD) is an irreversible age-related neurodegenerative disorder clinically characterized by severe memory impairment, language deficits and cognitive decline. The major neuropathological hallmarks of AD include extracellular deposits of the β-amyloid (Aβ) peptides and cytoplasmic...

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Detalles Bibliográficos
Autores principales: Maggiore, Anna, Casale, Assunta Maria, Toscanelli, Walter, Cappucci, Ugo, Rotili, Dante, Grieco, Maddalena, Gagné, Jean-Philippe, Poirier, Guy G., d’Erme, Maria, Piacentini, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027574/
https://www.ncbi.nlm.nih.gov/pubmed/35455964
http://dx.doi.org/10.3390/cells11081284