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Sensitive Assay for the Lactonase Activity of Serum Paraoxonase 1 (PON1) by Harnessing the Fluorescence Turn-On Characteristics of Bioorthogonally Synthesized and Geometrically Controlled Chemical Probes

The lactonase activity of paraoxonase 1 (PON1) has a crucial antiatherogenic function, and also serves as an important biochemical marker in human blood because the aberrant lactonase activity of PON1 is a key indicator for a number of diverse human diseases. However, no sensitive fluorescence assay...

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Detalles Bibliográficos
Autores principales:	Fang, Bo-Kai, Dai, Chia-Yen, Severance, Scott, Hwang, Chi-Ching, Huang, Chien-Hui, Hou, Sin-Yu, Yeh, Bao-Lin, Gong, Ming-Mao, Chou, Yun-Hao, Wang, Jeh-Jeng, Wang, Tzu-Pin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027646/ https://www.ncbi.nlm.nih.gov/pubmed/35458635 http://dx.doi.org/10.3390/molecules27082435

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