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Combination of LIGHT (TNFSF14)-Armed Myxoma Virus Pre-Loaded into ADSCs and Gemcitabine in the Treatment of Experimental Orthotopic Murine Pancreatic Adenocarcinoma

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is a weakly immunogenic fatal neoplasm. Oncolytic viruses have dual anti-cancer properties including tumor-lysing and immune response-boosting effects and offer attractive alternative for PDAC management. Adipose-derived stem cells (AD-SCs) of...

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Detalles Bibliográficos
Autores principales:	Jazowiecka-Rakus, Joanna, Sochanik, Aleksander, Hadryś, Agata, Fidyk, Wojciech, Chmielik, Ewa, Rahman, Masmudur M., McFadden, Grant
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027757/ https://www.ncbi.nlm.nih.gov/pubmed/35454928 http://dx.doi.org/10.3390/cancers14082022

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