Quantification of Structural Integrity and Stability Using Nanograms of Protein by Flow-Induced Dispersion Analysis

In the development of therapeutic proteins, analytical assessment of structural stability and integrity constitutes an important activity, as protein stability and integrity influence drug efficacy, and ultimately patient safety. Existing analytical methodologies solely rely on relative changes in o...

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Detalles Bibliográficos
Autores principales: Pedersen, Morten E., Østergaard, Jesper, Jensen, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027858/
https://www.ncbi.nlm.nih.gov/pubmed/35458703
http://dx.doi.org/10.3390/molecules27082506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027858/
https://www.ncbi.nlm.nih.gov/pubmed/35458703
http://dx.doi.org/10.3390/molecules27082506

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