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Transcriptomic profiling of pemphigus lesion infiltrating mononuclear cells reveals a distinct local immune microenvironment and novel lncRNA regulators

Pemphigus is an autoimmune skin disease. Ectopic lymphoid-like structures (ELSs) were found to be commonly present in the pemphigus lesions, presumably supporting in situ desmoglein (Dsg)-specific antibody production. Yet functional phenotypes and the regulators of Lymphoid aggregates in pemphigus l...

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Detalles Bibliográficos
Autores principales: Huang, Zi-xuan, Qu, Peng, Wang, Kan-kan, Zheng, Jie, Pan, Meng, Zhu, Hai-qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027862/
https://www.ncbi.nlm.nih.gov/pubmed/35449056
http://dx.doi.org/10.1186/s12967-022-03387-7