Apolipoprotein C3-Rich Low-Density Lipoprotein Induces Endothelial Cell Senescence via FBXO31 and Its Inhibition by Sesamol In Vitro and In Vivo

Premature endothelial senescence decreases the atheroprotective capacity of the arterial endothelium. Apolipoprotein C3 (ApoC3) delays the catabolism of triglyceride-rich particles and plays a critical role in atherosclerosis progression. FBXO31 is required for the intracellular response to DNA dama...

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Detalles Bibliográficos
Autores principales: Tsai, Ping-Hsuan, Chen, Li-Zhen, Tseng, Kuo-Feng, Chen, Fang-Yu, Shen, Ming-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028166/
https://www.ncbi.nlm.nih.gov/pubmed/35453604
http://dx.doi.org/10.3390/biomedicines10040854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028166/
https://www.ncbi.nlm.nih.gov/pubmed/35453604
http://dx.doi.org/10.3390/biomedicines10040854

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