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Evolution of Bacterial Persistence to Antibiotics during a 50,000-Generation Experiment in an Antibiotic-Free Environment
Failure of antibiotic therapies causes > 700,000 deaths yearly and involves both bacterial resistance and persistence. Persistence results in the relapse of infections by producing a tiny fraction of pathogen survivors that stay dormant during antibiotic exposure. From an evolutionary perspective...
Autores principales: | Mathé-Hubert, Hugo, Amia, Rafika, Martin, Mikaël, Gaffé, Joël, Schneider, Dominique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028194/ https://www.ncbi.nlm.nih.gov/pubmed/35453204 http://dx.doi.org/10.3390/antibiotics11040451 |
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