Cargando…

Self-Assembling Peptide Hydrogels as Functional Tools to Tackle Intervertebral Disc Degeneration

Low back pain (LBP), caused by intervertebral disc (IVD) degeneration, is a major contributor to global disability. In its healthy state, the IVD is a tough and well-hydrated tissue, able to act as a shock absorber along the spine. During degeneration, the IVD is hit by a cell-driven cascade of even...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ligorio, Cosimo, Hoyland, Judith A., Saiani, Alberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028266/ https://www.ncbi.nlm.nih.gov/pubmed/35448112 http://dx.doi.org/10.3390/gels8040211

Ejemplares similares

Graphene oxide containing self-assembling peptide hybrid hydrogels as a potential 3D injectable cell delivery platform for intervertebral disc repair applications
por: Ligorio, Cosimo, et al.
Publicado: (2019)

Role of Sheet-Edge Interactions in β-sheet Self-Assembling Peptide Hydrogels
por: Wychowaniec, Jacek K., et al.
Publicado: (2020)

Incorporation of Natural and Recombinant Collagen Proteins within Fmoc-Based Self-Assembling Peptide Hydrogels
por: Vitale, Mattia, et al.
Publicado: (2022)

Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
por: Le Maitre, Christine Lyn, et al.
Publicado: (2007)

Modeling the Three-Dimensional Bioprinting Process of β-Sheet Self-Assembling Peptide Hydrogel Scaffolds
por: Chiesa, Irene, et al.
Publicado: (2020)

Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration
por: Millward-Sadler, S Jane, et al.
Publicado: (2009)

Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc
por: Purmessur, Devina, et al.
Publicado: (2008)

The role of interleukin-1 in the pathogenesis of human Intervertebral disc degeneration
por: Le Maitre, Christine Lyn, et al.
Publicado: (2005)

Importance of Matrix Cues on Intervertebral Disc Development, Degeneration, and Regeneration
por: Kibble, Matthew J., et al.
Publicado: (2022)

Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes
por: Minogue, Ben M, et al.
Publicado: (2010)

Expression of semaphorin 3A and its receptors in the human intervertebral disc: potential role in regulating neural ingrowth in the degenerate intervertebral disc
por: Tolofari, Sotonye K, et al.
Publicado: (2010)

Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration
por: Heathfield, Sarah Kathleen, et al.
Publicado: (2008)

Degeneration of the intervertebral disc
por: Urban, Jill PG, et al.
Publicado: (2003)

Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1β and TNFα expression profile
por: Le Maitre, Christine Lyn, et al.
Publicado: (2007)

Pathomechanism of intervertebral disc degeneration
por: Oichi, Takeshi, et al.
Publicado: (2020)

Treatment of Intervertebral Disc Degeneration
por: Xin, Jingguo, et al.
Publicado: (2022)

Macrophages and Intervertebral Disc Degeneration
por: Koroth, Jinsha, et al.
Publicado: (2023)

Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc
por: Richardson, Stephen M, et al.
Publicado: (2009)

Combinatorial conditioning of adipose derived‐mesenchymal stem cells enhances their neurovascular potential: Implications for intervertebral disc degeneration
por: Binch, Abbie. L. A., et al.
Publicado: (2019)

The Immune Privilege of the Intervertebral Disc: Implications for Intervertebral Disc Degeneration Treatment
por: Sun, Zhen, et al.
Publicado: (2020)

Degenerate intervertebral disc‐like pH induces a catabolic mechanoresponse in human nucleus pulposus cells
por: Hodson, Nathan W., et al.
Publicado: (2018)

Treatment outcomes of injectable thermosensitive hydrogel containing bevacizumab in intervertebral disc degeneration
por: Chen, Qian, et al.
Publicado: (2022)

Injectable bioorthogonal hydrogel (BIOGEL) accelerates tissue regeneration in degenerated intervertebral discs
por: Luo, Jeffrey, et al.
Publicado: (2022)

Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells
por: Le Maitre, Christine L, et al.
Publicado: (2009)

Applications of Functionalized Hydrogels in the Regeneration of the Intervertebral Disc
por: Yan, Caiping, et al.
Publicado: (2021)

The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration
por: Dudek, Michal, et al.
Publicado: (2017)

Acidic pH promotes intervertebral disc degeneration: Acid-sensing ion channel -3 as a potential therapeutic target
por: Gilbert, Hamish T. J., et al.
Publicado: (2016)

Identification of novel nucleus pulposus markers: Interspecies variations and implications for cell-based therapies for intervertebral disc degeneration
por: Rodrigues-Pinto, R., et al.
Publicado: (2013)

Intervertebral Disc Biology: Genetic Basis of Disc Degeneration
por: Munir, Sabrina, et al.
Publicado: (2018)

Injectable hydrogel with nucleus pulposus-matched viscoelastic property prevents intervertebral disc degeneration
por: Jia, Haoruo, et al.
Publicado: (2022)

Angiogenesis in the degeneration of the lumbar intervertebral disc
por: David, Gh, et al.
Publicado: (2010)

Intervertebral disc degeneration therapies in human
por: Richardson, Stephen M
Publicado: (2015)

Genetic factors in intervertebral disc degeneration
por: Feng, Yi, et al.
Publicado: (2016)

The Role of Adipokines in Intervertebral Disc Degeneration
por: Sharma, Anirudh
Publicado: (2018)

Molecular Mechanisms of Intervertebral Disc Degeneration
por: Rider, Sean M., et al.
Publicado: (2018)

Genetic Therapy for Intervertebral Disc Degeneration
por: Roh, Eun Ji, et al.
Publicado: (2021)

Cervical intervertebral disc degeneration and dizziness
por: Liu, Tang-Hua, et al.
Publicado: (2021)

The Proteolysis of ECM in Intervertebral Disc Degeneration
por: Liang, Huaizhen, et al.
Publicado: (2022)

The role of ferroptosis in intervertebral disc degeneration
por: Fan, Chunyang, et al.
Publicado: (2023)

Role of Necroptosis in Intervertebral Disc Degeneration
por: Khaleque, Md Abdul, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_tpp2nskveaiph8a4geaed0ijua