Lack of Functional Trehalase Activity in Candida parapsilosis Increases Susceptibility to Itraconazole

Central metabolic pathways may play a major role in the virulence of pathogenic fungi. Here, we have investigated the susceptibility of a Candida parapsilosis mutant deficient in trehalase activity (atc1Δ/ntc1Δ strain) to the azolic compounds fluconazole and itraconazole. A time-course exposure to i...

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Detalles Bibliográficos
Autores principales: Sánchez-Fresneda, Ruth, Muñoz-Megías, María Luz, Yagüe, Genoveva, Solano, Francisco, Maicas, Sergi, Argüelles, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028276/
https://www.ncbi.nlm.nih.gov/pubmed/35448602
http://dx.doi.org/10.3390/jof8040371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028276/
https://www.ncbi.nlm.nih.gov/pubmed/35448602
http://dx.doi.org/10.3390/jof8040371

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