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2-Pyridine Carboxaldehyde for Semi-Automated Soft Spot Identification in Cyclic Peptides

Cyclic peptides are an attractive option as therapeutics due to their ability to disrupt crucial protein–protein interactions and their flexibility in display type screening strategies, but they come with their own bioanalytical challenges in metabolite identification. Initial amide hydrolysis of a...

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Detalles Bibliográficos
Autores principales:	Zhang, Haiying, Chacko, Silvi, Cannon, Joe R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028278/ https://www.ncbi.nlm.nih.gov/pubmed/35457087 http://dx.doi.org/10.3390/ijms23084269

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