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Aluminium Gauze Reduces SARS-CoV-2 Viral Load in Non-Woven Masks Worn by Patients with COVID-19

Background: Aluminium reduces severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) survival in experimental settings. It is unknown whether adding an aluminium gauze to a mask reduces the SARS-CoV-2 RNA load in the mask and whether SARS-CoV-2 is detectable in the breath that permeates throug...

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Autores principales: Yasuda, Yuto, Mutsuo, Satoru, Hamada, Motoaki, Murai, Kazuo, Hirayama, Yutaka, Uemasu, Kiyoshi, Arasawa, Soichi, Iwashima, Daisuke, Takahashi, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028381/
https://www.ncbi.nlm.nih.gov/pubmed/35447882
http://dx.doi.org/10.3390/idr14020030
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author Yasuda, Yuto
Mutsuo, Satoru
Hamada, Motoaki
Murai, Kazuo
Hirayama, Yutaka
Uemasu, Kiyoshi
Arasawa, Soichi
Iwashima, Daisuke
Takahashi, Ken-ichi
author_facet Yasuda, Yuto
Mutsuo, Satoru
Hamada, Motoaki
Murai, Kazuo
Hirayama, Yutaka
Uemasu, Kiyoshi
Arasawa, Soichi
Iwashima, Daisuke
Takahashi, Ken-ichi
author_sort Yasuda, Yuto
collection PubMed
description Background: Aluminium reduces severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) survival in experimental settings. It is unknown whether adding an aluminium gauze to a mask reduces the SARS-CoV-2 RNA load in the mask and whether SARS-CoV-2 is detectable in the breath that permeates through such a mask in clinical settings. Methods: Patients admitted to Kishiwada City Hospital, Osaka, Japan, between July 2021 and September 2021 were enrolled in the study. Non-woven masks comprising filters with 99% viral filtration efficacy and aluminium and cotton gauzes attached to plastic collection cases were developed. All participants wore the experimental mask models for three hours. Results: Twenty-nine patients who wore the final model masks were analysed in this study. The Ct values of the nucleocapsid gene and envelope gene of SARS-CoV-2 were significantly higher in the aluminium gauze than in the cotton gauze. SARS-CoV-2 RNA was detected in the masks of 8 out of 12 vaccinated patients (66.7%). Although breath condensates were collected behind both aluminium and cotton gauzes, SARS-CoV-2 RNA was not detected in these condensates. Conclusions: Our study indicated that non-woven masks with an aluminium gauze may obstruct SARS-CoV-2 transmission in clinical settings better than non-woven masks with cotton gauzes.
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spelling pubmed-90283812022-04-23 Aluminium Gauze Reduces SARS-CoV-2 Viral Load in Non-Woven Masks Worn by Patients with COVID-19 Yasuda, Yuto Mutsuo, Satoru Hamada, Motoaki Murai, Kazuo Hirayama, Yutaka Uemasu, Kiyoshi Arasawa, Soichi Iwashima, Daisuke Takahashi, Ken-ichi Infect Dis Rep Article Background: Aluminium reduces severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) survival in experimental settings. It is unknown whether adding an aluminium gauze to a mask reduces the SARS-CoV-2 RNA load in the mask and whether SARS-CoV-2 is detectable in the breath that permeates through such a mask in clinical settings. Methods: Patients admitted to Kishiwada City Hospital, Osaka, Japan, between July 2021 and September 2021 were enrolled in the study. Non-woven masks comprising filters with 99% viral filtration efficacy and aluminium and cotton gauzes attached to plastic collection cases were developed. All participants wore the experimental mask models for three hours. Results: Twenty-nine patients who wore the final model masks were analysed in this study. The Ct values of the nucleocapsid gene and envelope gene of SARS-CoV-2 were significantly higher in the aluminium gauze than in the cotton gauze. SARS-CoV-2 RNA was detected in the masks of 8 out of 12 vaccinated patients (66.7%). Although breath condensates were collected behind both aluminium and cotton gauzes, SARS-CoV-2 RNA was not detected in these condensates. Conclusions: Our study indicated that non-woven masks with an aluminium gauze may obstruct SARS-CoV-2 transmission in clinical settings better than non-woven masks with cotton gauzes. MDPI 2022-04-06 /pmc/articles/PMC9028381/ /pubmed/35447882 http://dx.doi.org/10.3390/idr14020030 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yasuda, Yuto
Mutsuo, Satoru
Hamada, Motoaki
Murai, Kazuo
Hirayama, Yutaka
Uemasu, Kiyoshi
Arasawa, Soichi
Iwashima, Daisuke
Takahashi, Ken-ichi
Aluminium Gauze Reduces SARS-CoV-2 Viral Load in Non-Woven Masks Worn by Patients with COVID-19
title Aluminium Gauze Reduces SARS-CoV-2 Viral Load in Non-Woven Masks Worn by Patients with COVID-19
title_full Aluminium Gauze Reduces SARS-CoV-2 Viral Load in Non-Woven Masks Worn by Patients with COVID-19
title_fullStr Aluminium Gauze Reduces SARS-CoV-2 Viral Load in Non-Woven Masks Worn by Patients with COVID-19
title_full_unstemmed Aluminium Gauze Reduces SARS-CoV-2 Viral Load in Non-Woven Masks Worn by Patients with COVID-19
title_short Aluminium Gauze Reduces SARS-CoV-2 Viral Load in Non-Woven Masks Worn by Patients with COVID-19
title_sort aluminium gauze reduces sars-cov-2 viral load in non-woven masks worn by patients with covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028381/
https://www.ncbi.nlm.nih.gov/pubmed/35447882
http://dx.doi.org/10.3390/idr14020030
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